Peter Jenner Selected Research

Levodopa (L Dopa)

1/2021	Redefining the strategy for the use of COMT inhibitors in Parkinson's disease: the role of opicapone.
11/2020	Improving the Delivery of Levodopa in Parkinson's Disease: A Review of Approved and Emerging Therapies.
12/2019	Reply to: "Parkinson disease-associated dyskinesia in countries with low access to levodopa-sparing Regimens".
12/2019	Can therapeutic strategies prevent and manage dyskinesia in Parkinson's disease? An update.
1/2019	Should there be less emphasis on levodopa-induced dyskinesia in Parkinson's disease?
11/2018	The treatment of levodopa-induced dyskinesias: Surfing the serotoninergic wave.
4/2018	The effect of Banisteriopsis caapi (B. caapi) on the motor deficits in the MPTP-treated common marmoset model of Parkinson's disease.
1/2017	Hallmarks of Treatment Aspects: Parkinson's Disease Throughout Centuries Including l-Dopa.
1/2016	Oral r-(-)-11-o-valeryl-n-n-propylnoraporphine reverses motor deficits in mptp-treated marmosets.
11/2015	The adenosine A2A receptor antagonist, istradefylline enhances anti-parkinsonian activity induced by combined treatment with low doses of L-DOPA and dopamine agonists in MPTP-treated common marmosets.

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Peter Jenner Research Topics

Disease

94	Parkinson Disease (Parkinson's Disease) 04/2022 - 02/2002
56	Dyskinesias (Dyskinesia) 11/2020 - 02/2002
8	Inflammation (Inflammations) 01/2021 - 01/2003
5	Neurodegenerative Diseases (Neurodegenerative Disease) 04/2022 - 10/2002
5	Disease Progression 01/2022 - 01/2009
5	Chorea (Rheumatic Chorea) 12/2006 - 09/2002
4	Mitochondrial Diseases (Mitochondrial Disease) 09/2013 - 01/2003
4	Dystonia (Limb Dystonia) 12/2006 - 09/2003
2	Restless Legs Syndrome (Restless Legs) 01/2021 - 11/2014
2	Cognitive Dysfunction 11/2020 - 12/2013
2	Lewy Body Disease (Lewy Body Dementia) 12/2012 - 06/2008
2	Dementia (Dementias) 06/2008 - 12/2002
2	Parkinsonian Disorders (Parkinsonism) 12/2006 - 08/2002
2	Infections 11/2004 - 10/2004
2	Hypokinesia (Bradykinesia) 06/2004 - 01/2003
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 07/2003 - 10/2002
1	Ganglion Cysts (Ganglion) 01/2021
1	Sleepiness 11/2020
1	Disorders of Excessive Somnolence (Hypersomnia) 11/2020
1	Phobic Disorders (Phobia) 01/2020
1	Sensation Disorders 01/2017
1	Abnormal Reflex (Hyperreflexia) 01/2017
1	Anhidrotic Ectodermal Dysplasia 1 01/2015
1	Iron Deficiencies 11/2014
1	Vomiting 10/2014

Drug/Important Bio-Agent (IBA)

60	Levodopa (L Dopa)FDA LinkGeneric 01/2021 - 02/2002
38	1- Methyl- 4- phenyl- 1,2,3,6- tetrahydropyridine (MPTP)IBA 04/2018 - 02/2002
24	Pharmaceutical PreparationsIBA 11/2020 - 02/2002
24	Dopamine Agonists (Dopamine Agonist)IBA 01/2020 - 02/2002
21	Dopamine (Intropin)FDA LinkGeneric 11/2020 - 04/2002
11	Proteins (Proteins, Gene)FDA Link 02/2014 - 08/2002
8	Adenosine A2A Receptor (Adenosine A2A Receptors)IBA 04/2022 - 06/2005
8	istradefyllineIBA 01/2021 - 12/2003
8	Dopamine Agents (Dopaminergic Agents)IBA 01/2015 - 09/2002
7	Dopamine Receptors (Dopamine Receptor)IBA 07/2013 - 09/2002
6	Oxidopamine (6 Hydroxydopamine)IBA 10/2013 - 09/2010
6	Pramipexole (Mirapex)FDA LinkGeneric 02/2010 - 10/2003
5	Adenosine (Adenocard)FDA LinkGeneric 01/2021 - 12/2011
5	Apomorphine FDA Link 12/2018 - 01/2003
5	Proteasome Endopeptidase Complex (Proteasome)IBA 12/2012 - 07/2002
4	Adenosine A2 Receptor AntagonistsIBA 04/2022 - 01/2014
4	ropinirole (Requip)FDA LinkGeneric 01/2015 - 03/2007
4	Serotonin (5 Hydroxytryptamine)IBA 07/2014 - 10/2003
4	OsteopontinIBA 08/2013 - 12/2004
4	Nitric Oxide (Nitrogen Monoxide)FDA Link 12/2011 - 08/2002
4	Carbidopa (Lodosyn)FDA LinkGeneric 06/2010 - 03/2005
4	entacapone (Comtan)FDA Link 12/2007 - 05/2003
3	rotigotine FDA Link 01/2021 - 07/2005
3	Neuroprotective AgentsIBA 01/2020 - 10/2011
3	Amantadine (Aman)FDA LinkGeneric 12/2019 - 12/2011
3	Nitric Oxide Synthase Type I (Neuronal Nitric Oxide Synthase)IBA 06/2015 - 08/2011
3	Nitric Oxide Synthase Type II (Inducible Nitric Oxide Synthase)IBA 06/2015 - 11/2004
3	Tyrosine 3-Monooxygenase (Tyrosine Hydroxylase)IBA 01/2015 - 11/2003
3	LipopolysaccharidesIBA 08/2013 - 08/2008
3	UbiquitinIBA 12/2012 - 08/2002
3	BenserazideIBA 04/2012 - 04/2007
3	Superoxide Dismutase-1IBA 07/2003 - 10/2002
2	Monoamine Oxidase (MAO)IBA 01/2022 - 10/2004
2	Pergolide (Permax)FDA Link 01/2015 - 01/2003
2	1-Methyl-4-phenylpyridinium (1 Methyl 4 phenylpyridinium)IBA 01/2015 - 12/2004
2	Glial Fibrillary Acidic ProteinIBA 01/2015 - 04/2005
2	N-Methylaspartate (NMDA)IBA 12/2011 - 05/2004
2	catechol (pyrocatechol)IBA 12/2007 - 01/2003
2	NeuropeptidesIBA 04/2007 - 02/2003
2	2- n- butyl- 9- methyl- 8- (1,2,3)triazol- 2- yl- 9H- purin- 6- ylamineIBA 02/2007 - 09/2006
2	Piribedil (Trivastal)IBA 05/2006 - 09/2002
2	Haloperidol (Haldol)FDA LinkGeneric 11/2004 - 12/2003
2	Messenger RNA (mRNA)IBA 11/2003 - 02/2003
2	PiperazineIBA 09/2002 - 09/2002
1	Choline O-Acetyltransferase (Choline Acetyltransferase)IBA 01/2021
1	SynucleinsIBA 01/2021
1	Carbachol (Carbastat)FDA Link 01/2021
1	Vasoactive Intestinal Peptide (VIP (Vasoactive Intestinal Peptide))IBA 01/2021
1	opicaponeIBA 01/2021
1	Biological FactorsIBA 01/2020
1	Metformin (Glucophage)FDA LinkGeneric 01/2020
1	Uric Acid (Urate)IBA 01/2020
1	Hydrocortisone (Cortisol)FDA LinkGeneric 01/2020
1	Harmine (Telepathine)IBA 04/2018
1	Selegiline (E250)FDA LinkGeneric 04/2018
1	Cysteine Proteinase InhibitorsIBA 01/2017
1	Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA 01/2017
1	Cholinergic Antagonists (Anticholinergics)IBA 01/2017
1	Cystatin CIBA 01/2017
1	11-hydroxy-N-(n-propyl)noraporphineIBA 01/2016
1	ValeratesIBA 01/2016
1	IronIBA 11/2014
1	Histamine AgonistsIBA 10/2014
1	4-(1H-imidazol-4-ylmethyl)piperidineIBA 10/2014
1	Histamine H3 Receptors (Histamine H3 Receptor)IBA 10/2014
1	Dizocilpine Maleate (Dizocilpine)IBA 10/2014

Therapy/Procedure

18	Therapeutics 11/2020 - 01/2003
3	Oral Administration 01/2016 - 05/2006
2	Subcutaneous Infusions 12/2016 - 01/2016
2	Pallidotomy 12/2011 - 09/2005
2	Denervation 09/2008 - 09/2003
1	Transdermal Patch 01/2021
1	Deep Brain Stimulation 12/2019
1	Precision Medicine 12/2019
1	Subcutaneous Injections 01/2016